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A Method of Nodose Ganglia Injection in Sprague-Dawley Rat
Chapters
- 00:05Title
- 01:24Preparation of Instruments and Chemicals
- 02:31Catherization of the Femoral Vein
- 04:00Serotonin–induced Apnea via IV Infusion
- 05:45Neck Surgery to Expose Nodose Ganglia
- 08:18Results: Respiratory Recordings after Serotonin Induction of Apnea Before and After Intranodose Ganglia Injections of Dronabinol
- 08:57Conclusion
Afferent vagal signaling transmits important information to central nervous system from receptors located in organs of the abdomen and thorax. The nodose ganglia of vagus nerves contain many types of receptors that modulate vagal activity. This protocol describes a method of local injections of neurochemicals into the nodose ganglia.
