Journal
/
工程学
/
Coherent anti-Stokes Raman Scattering (CARS) Microscopía visualiza Tablets Farmacéuticos durante la disolución
JoVE 杂志
工程学
This content is Free Access.
JoVE 杂志 工程学
Coherent anti-Stokes Raman Scattering (CARS) Microscopy Visualizes Pharmaceutical Tablets During Dissolution
Please note that all translations are automatically generated. Click here for the English version.

Coherent anti-Stokes Raman Scattering (CARS) Microscopía visualiza Tablets Farmacéuticos durante la disolución

17,740 Views

•

09:59 min

•

July 04, 2014

DOI:

10.3791/51847-v

DOI:
10.3791/51847-v

•

09:59 min
July 04, 2014

•

3 Views
, , , ,
1Optical Sciences Group, MESA+ Institute,University of Twente, 2Institute of Pharmaceutics and Biopharmaceutics,Heinrich-Heine University, 3Division of Pharmaceutical Technology, Faculty of Pharmacy,University of Helsinki

Summary

Automatically generated

Anti-Stokes dispersión Raman (CARS) microscopía coherente se combina con una configuración de disolución de flujo a través intrínseca para permitir in situ y visualización en tiempo real de la superficie de comprimidos farmacéuticos sometidos a la disolución. Utilizando esta configuración a la medida, es posible correlacionar COCHES vídeos con perfiles de disolución de fármacos grabados mediante espectroscopía de absorción UV inline.

Explore More Videos

Coherent Anti-Stokes Raman Scattering (CARS) MicroscopyPharmaceutical TabletsDissolutionTheophylline AnhydrateEthyl CelluloseTheophylline MonohydrateUV Absorption SpectroscopyDissolution RateSurface CompositionSurface Structure

Read Article

Cite this Article

Fussell, A. L., Kleinebudde, P., Herek, J., Strachan, C. J., Offerhaus, H. L. Coherent anti-Stokes Raman Scattering (CARS) Microscopy Visualizes Pharmaceutical Tablets During Dissolution. J. Vis. Exp. (89), e51847, doi:10.3791/51847 (2014).

Download .ris file

Copy

Share Video

.

Copy