/

/

相干反斯托克斯拉曼散射（CARS）显微可视化药片剂溶出过程中

JoVE 杂志
工程学

This content is Free Access.

JoVE 杂志工程学

Coherent anti-Stokes Raman Scattering (CARS) Microscopy Visualizes Pharmaceutical Tablets During Dissolution

Please note that all translations are automatically generated. Click here for the English version.

相干反斯托克斯拉曼散射（CARS）显微可视化药片剂溶出过程中

17,740 Views

•

09:59 min

•

July 04, 2014

DOI:

10.3791/51847-v

DOI:

10.3791/51847-v

•

09:59 min

July 04, 2014

•

3 Views

Andrew L. Fussell¹, Peter Kleinebudde², Jennifer Herek¹, Clare J. Strachan³, Herman L. Offerhaus¹

¹Optical Sciences Group, MESA+ Institute,University of Twente, ²Institute of Pharmaceutics and Biopharmaceutics,Heinrich-Heine University, ³Division of Pharmaceutical Technology, Faculty of Pharmacy,University of Helsinki

Summary

相干反斯托克斯拉曼散射（CARS）显微术是结合本征流通过溶解的设置，以允许在原位和药物片剂进行溶出度的表面的实时可视化。使用这种定制的设置，因此能够使用内联紫外吸收光谱记录药物溶出曲线相关CARS视频。

Explore More Videos

Coherent Anti-Stokes Raman Scattering (CARS) Microscopy Pharmaceutical Tablets Dissolution Theophylline Anhydrate Ethyl Cellulose Theophylline Monohydrate UV Absorption Spectroscopy Dissolution Rate Surface Composition Surface Structure

Read Article