La conformité à l'exercice forcé chez les rongeurs: Une norme critique pour évaluer l'impact d'exercice dans les troubles liés au vieillissement et la maladie
La conformité à l'exercice forcé chez les rongeurs: Une norme critique pour évaluer l'impact d'exercice dans les troubles liés au vieillissement et la maladie
Exercise may alleviate behavioral impairments associated with neurodegenerative diseases. Studies of the mechanisms underlying exercise-mediated effects have increased in disease models, but the neurobiological background accompanying these diseases, specifically aging, is likely not considered. Here, we illustrate measures to increase the likelihood of a successful exercise paradigm in aged rats.
Arnold, J. C., Salvatore, M. F. Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease. J. Vis. Exp. (90), e51827, doi:10.3791/51827 (2014).