Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
Bölümler
- 00:05Başlık
- 02:01Baseline Locomotor Activity Assessments: Determining Forced Exercise Group Assignments
- 04:08Acclimation on the Treadmill
- 06:32Treadmill Exercise Training
- 07:36Representative Results: Evaluation of Baseline Locomotor Activity, Treadmill Exercise Scores, and Body Weight
- 09:17Conclusion
Exercise may alleviate behavioral impairments associated with neurodegenerative diseases. Studies of the mechanisms underlying exercise-mediated effects have increased in disease models, but the neurobiological background accompanying these diseases, specifically aging, is likely not considered. Here, we illustrate measures to increase the likelihood of a successful exercise paradigm in aged rats.
