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Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice
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July 25, 2014
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Tail-skin transplantation is a powerful model for studying T cell-dependent rejection and tolerance induction during allogeneic immune responses in mice. The advantages of this protocol are minor invasive surgery, and ease of monitoring with no need to sacrifice the recipient mouse.
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Schmaler, M., Broggi, M. A. S., Rossi, S. W. Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice. J. Vis. Exp. (89), e51724, doi:10.3791/51724 (2014).
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