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Mouse Hindbrain Ex Vivo Culture to Study Facial Branchiomotor Neuron Migration
JoVE 杂志
神经科学
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JoVE 杂志 神经科学
Mouse Hindbrain Ex Vivo Culture to Study Facial Branchiomotor Neuron Migration

Mouse Hindbrain Ex Vivo Culture to Study Facial Branchiomotor Neuron Migration

10,918 Views

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10:57 min

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March 18, 2014

DOI:

10.3791/51397-v

DOI:
10.3791/51397-v

•

10:57 min
March 18, 2014

•

2 Views
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1UCL Institute of Ophthalmology,University College London, 2Department of Human Immunology,Centre for Cancer Biology, South Australia

Summary

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Embryonic neurons are born in the ventricular zone of the neural tube, but migrate to reach appropriate targets. Facial branchiomotor (FBM) neurons are a useful model to study neuronal migration. This protocol describes the wholemount ex vivo culture of mouse embryo hindbrains to investigate mechanisms that regulate FBM migration.

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Cite this Article

Tillo, M., Schwarz, Q., Ruhrberg, C. Mouse Hindbrain Ex Vivo Culture to Study Facial Branchiomotor Neuron Migration. J. Vis. Exp. (85), e51397, doi:10.3791/51397 (2014).

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