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In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves
JoVE 杂志
神经科学
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JoVE 杂志 神经科学
In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves

In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves

DOI:
10.3791/51181-v

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11:07 min

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April 13, 2014

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, , ,
1Leibniz Institute for Age Research,Fritz Lipmann Institute, 2Friedrich Schiller University Jena, 3Institute of Molecular Cell Biology & Center for Sepsis Control and Care (CSCC) Jena University Hospital,Friedrich Schiller University Jena

Chapters

  • 00:00Title
  • 01:16Introduction
  • 01:58Experimental Setup
  • 06:01Measurements
  • 07:39Data Analysis
  • 09:59Conclusion

Summary

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Measurements of nerve conduction properties in vivo exemplify a powerful tool to characterize various animal models of neuromuscular diseases. Here, we present an easy and reliable protocol by which electrophysiological analysis on sciatic nerves of anesthetized mice can be performed.

Tags

Keywords: In VivoElectrophysiologyMouseSciatic NerveNerve Conduction VelocityCompound Motor Action PotentialAnesthesiaBody TemperatureElectrocardiogramPeripheral Nervous System

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