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Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion
JoVE 杂志
医学
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JoVE 杂志 医学
Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion
DOI:

05:59 min

March 03, 2014

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Chapters

  • 00:05Title
  • 02:06Rectal Probe Doppler Placement
  • 02:54Dissection of Aortic Arch/Subclavian Artery
  • 04:59Representative Thoracic Aortic Occlusion-induced Paraplegia Results
  • 05:38Conclusion

Summary

自动翻译

The lack of mechanistic understanding of spinal cord ischemia-reperfusion injury has hindered further adjuncts to prevent paraplegia following high risk aortic operations. Thus, the development of animal models is imperative. This manuscript demonstrates reproducible lower extremity paralysis following thoracic aortic occlusion in a murine model.

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