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Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
JoVE 杂志
医学
Author Produced
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JoVE 杂志 医学
Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion

Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion

DOI:
10.3791/50214-v

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12:15 min

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February 17, 2013

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, , , , , , , , , ,
1Department of Neuroscience and Biomedical Technologies,University of Milano Bicocca

Chapters

  • 00:05Title
  • 01:17Cerebral perfusion monitoring
  • 02:43Probe holder preparation
  • 05:07Presurgical preparation
  • 05:47Probe positioning and securing
  • 09:26Cerebral perfusion monitoring during MCAO
  • 10:15Representative results
  • 11:48Conclusion

Summary

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Cerebral perfusion monitoring has been demonstrated to improve accuracy in ischemic stroke models. Technical difficulties often limit the use of this essential tool for cerebrovascular research. In this video, an optimized system is shown to obtain a single or multi-site hemodynamic monitoring during intraluminal middle cerebral artery occlusion in rats.

Tags

Cerebral Perfusion MonitoringLaser DopplerMiddle Cerebral Artery OcclusionRat Stroke ModelIntraluminal FilamentCustom Probe HolderMulti-site MonitoringAcute Ischemic StrokeCollateral Circulation

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