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Hyperpolarized Xenon for NMR and MRI Applications
JoVE 杂志
工程学
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JoVE 杂志 工程学
Hyperpolarized Xenon for NMR and MRI Applications
DOI:

16:20 min

September 06, 2012

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Chapters

  • 00:05Title
  • 01:48Preparation of the Spin Exchange Optical Pumping (SEOP) Setup
  • 06:56NMR Setup and Hyperpolarization Quantification
  • 09:51Functionalized Xenon Solution State Spectroscopy
  • 11:21Hyper-Chemical Exchange Saturation Transfer (CEST) Imaging
  • 14:06Results: Spectra Resulting from Hyperpolarized Xenon Use
  • 15:33Conclusion

Summary

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The production of hyperpolarized xenon by means of spin exchange optical pumping (SEOP) is described. This method yields a ~10000-fold enhancement of the nuclear spin polarization of Xe-129 and has applications in nuclear magnetic resonance spectroscopy and imaging. Examples of gas phase and solution state experiments are given.

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