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Expansão do sangue periférico humano γδ células T usando zoledronato
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13:08 min
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September 09, 2011
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Human Peripheral Bloodγδ T CellsExpansionZoledronateStress-induced AntigensAnti-tumor ActivityAnti-infective ActivityVγ9Vδ2 T Cell ReceptorMajor Histocompatibility Complex-independentCytolytic FunctionsTh1-like Effector FunctionsCancer ImmunotherapyPhosphoantigens(E)-4-hydroxy-3-methyl-but-2-enyl Pyrophosphate (HMBPP)Isoprenoid BiosynthesisIsopentenyl Pyrophosphate (IPP)Mevalonate PathwayDysregulationTumor CellsAminobisphosphonatesPamidronateFarnesyl Pyrophosphate Synthase (FPPS)Intracellular Levels Of IPP
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Kondo, M., Izumi, T., Fujieda, N., Kondo, A., Morishita, T., Matsushita, H., Kakimi, K. Expansion of Human Peripheral Blood γδ T Cells using Zoledronate. J. Vis. Exp. (55), e3182, doi:10.3791/3182 (2011).
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