Journal
/
神经科学
/
Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice
JoVE 杂志
神经科学
This content is Free Access.
JoVE 杂志 神经科学
Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

DOI:
10.3791/2920-v

•

07:02 min

•

July 20, 2011

•

, ,
1Department of Psychiatry, Brain Research Center,University of British Columbia

Chapters

  • 00:05Title
  • 01:27Equipment Preparation
  • 02:03Software Preparation
  • 02:54Day 1: Visible Platform
  • 04:14Day 2-5: Hidden Platform
  • 04:47Day 6: Probe Trial
  • 05:13Data Analysis
  • 05:37VPA’s Effect on Memory Deficits in the APP23 AD Mouse Model
  • 06:28Conclusion

Summary

自动翻译

自动翻译

The Morris Water Maze is a behavioral task to test hippocampal-dependent learning and memory. It has been widely used in the study of neurobiology, neuropharmacology and neurocognitive disorders in rodent models.

Tags

Morris Water Maze TestLearning DeficitsMemory DeficitsAlzheimer’s Disease Model MiceNeuroscientist Richard G. MorrisSpatial Memory AcquisitionLong-term Spatial MemoryHidden-platform ConditionVisible Platform ConditionOdor Trail InterferenceNeurobiologyNeuropharmacologyRodent Models For Neurocognitive DisordersAlzheimer’s Disease Transgenic Model Mice

Article

Embed

添加到播放列表

Usage Statistics

Related Videos

Low-stress Route Learning Using the Lashley III Maze in Mice

Design and Construction of a Cost Effective Headstage for Simultaneous Neural Stimulation and Recording in the Water Maze

C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays

Assaying Locomotor, Learning, and Memory Deficits in Drosophila Models of Neurodegeneration

T-maze Forced Alternation and Left-right Discrimination Tasks for Assessing Working and Reference Memory in Mice

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits

Assessing Spatial Learning and Memory in Small Squamate Reptiles

Read Article