Voice disorders are debilitating in aging and Parkinson disease. The ultrasonic vocalizations of rats, also affected by these conditions, can be used to study these voice disorders, their neural substrates, and the nature of functional recovery with behavioral intervention.
Johnson, A. M., Doll, E. J., Grant, L. M., Ringel, L., Shier, J. N., Ciucci, M. R. Targeted Training of Ultrasonic Vocalizations in Aged and Parkinsonian Rats. J. Vis. Exp. (54), e2835, doi:10.3791/2835 (2011).