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चूहे और ट्रांसजेनिक चूहों से एजिंग और Amyloid पैथोलॉजी के दौरान Synaptic बदलाव के अध्ययन के लिए तीव्र hippocampal स्लाइस की तैयारी
JoVE 杂志
神经科学
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JoVE 杂志 神经科学
Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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चूहे और ट्रांसजेनिक चूहों से एजिंग और Amyloid पैथोलॉजी के दौरान Synaptic बदलाव के अध्ययन के लिए तीव्र hippocampal स्लाइस की तैयारी

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14:57 min

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March 23, 2011

DOI:

10.3791/2330-v

DOI:
10.3791/2330-v

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14:57 min
March 23, 2011

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2 Views
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1Graduate Center for Gerontology,University of Kentucky College of Public Health, 2Department of Molecular and Biomedical Pharmacology,University of Kentucky College of Medicine, 3Sanders-Brown Center on Aging,University of Kentucky College of Medicine

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Acute Hippocampal SlicesRatsTransgenic MiceSynaptic AlterationsAgingAmyloid PathologySynaptic FunctionPlasticityElectrophysiological TechniquesCognitive ImpairmentsSynaptic Plasticity MechanismsLong-term PotentiationLong-term DepressionNootropic CompoundsBrain AgingAlzheimer’s Disease (AD)Aged RatsAD Model Mice

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Mathis, D. M., Furman, J. L., Norris, C. M. Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology. J. Vis. Exp. (49), e2330, doi:10.3791/2330 (2011).

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