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A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

JoVE 杂志
神经科学

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JoVE 杂志神经科学

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

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07:33 min

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May 21, 2010

DOI:

DOI:

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07:33 min

May 21, 2010

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6 Views

Stephan J. Guyenet, Stephanie A. Furrer, Vincent M. Damian, Travis D. Baughan, Albert R. La Spada*³, Gwenn A. Garden*²

¹Department of Biochemistry,University of Washington, ²Department of Neurology,University of Washington, ³Division of Genetics, Departments of Pediatrics and Cellular and Molecular Medicine, and the Institute for Genomic Medicine,University of California, San Diego – Rady Children’s Hospital

Tags

Composite Phenotype Scoring System Mouse Models Cerebellar Ataxia Phenotype Assessments Disease Severity Hind Limb Clasping Ledge Test Gait Kyphosis Neurodegenerative Disease Phenotypes Temporal Progression Transgenic Mouse Model Spinocerebellar Ataxia Type 7 (SCA7)Albert R. La Spada Gwenn A. Garden

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