When a susceptible host acquires a pathogen, the infection typically progresses through four main stages: incubation, prodromal stage, illness, and convalescence. These stages are of varying duration, depending on the type of pathogen. The incubation stage is the period from exposure to a pathogen until symptoms appear. Here, the pathogens grow and multiply within the body, but the infected person remains asymptomatic. In the prodromal stage, the pathogen replicates further, and the body's immune response is activated, resulting in mild symptoms such as fatigue, and the infection may spread. During the illness stage, the individual exhibits evident localized or systemic symptoms. Localized symptoms affect only one body part, for example, an abscess on the leg. Conversely, systemic symptoms affect the entire body and are commonly observed with infections such as influenza. As the illness stage progresses, the immune system continues to fight the infection, and the symptoms should progressively improve. However, secondary infections may occur if the primary infection has impaired the immune system. The patient returns to regular daily functioning during convalescence, while some disorders may cause permanent impairment.