ATP-driven pumps are a class of membrane proteins that use the energy from ATP hydrolysis to pump the solutes against their concentration gradient. Their basic structure includes transmembrane domains linked to the ATP-binding domains. These pumps are present across all domains of life, from bacteria to plants to animals, and are divided into four main types: P-type, ATP-binding cassette transporters, or ABC transporters, F-type, and V-type pumps. The P-type pumps transport protons and ions across the cell membrane. The most common examples include sodium-potassium pumps and calcium pumps. The ABC transporters can transport a diverse range of solutes, including amino acids, sugar, and lipids. The F-type pumps are found on the inner membrane of the mitochondria, plasma membrane of the bacteria, and thylakoid membrane of the chloroplasts. They move the protons down their concentration gradient and use the energy released to synthesize ATP, hence, they are also known as ATP synthases. The V-type pumps use energy from ATP hydrolysis to transport protons to acidify the lumen of plant vacuoles, lysosomes, and endosomes.