Yanrong Qian Edison Biotechnology Institute Ohio University Biography Publications Institution JoVE Articles Yanrong Qian has not added a biography. If you are Yanrong Qian and would like to personalize this page please email our Author Liaison for assistance. Publications A Small-molecule Pan-class I Glucose Transporter Inhibitor Reduces Cancer Cell Proliferation in Vitro and Tumor Growth in Vivo by Targeting Glucose-based Metabolism Cancer & Metabolism. Mar, 2021 | Pubmed ID: 33771231 Natural Compound α-PGG and Its Synthetic Derivative 6Cl-TGQ Alter Insulin Secretion: Evidence for Diminishing Glucose Uptake As a Mechanism Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy. 2021 | Pubmed ID: 33658814 Mouse Models of Growth Hormone Insensitivity Reviews in Endocrine & Metabolic Disorders. Mar, 2021 | Pubmed ID: 33037595 Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo Cancers. Dec, 2020 | Pubmed ID: 33291663 Differential Gene Signature in Adipose Tissue Depots of Growth Hormone Transgenic Mice Journal of Neuroendocrinology. 11, 2020 | Pubmed ID: 33043505 Isosteres of Ester Derived Glucose Uptake Inhibitors Bioorganic & Medicinal Chemistry Letters. 09, 2020 | Pubmed ID: 32736210 The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH? Endocrinology. 08, 2020 | Pubmed ID: 32556100 Growth Hormone Upregulates Melanocyte-Inducing Transcription Factor Expression and Activity Via JAK2-STAT5 and SRC Signaling in GH Receptor-Positive Human Melanoma Cancers. Sep, 2019 | Pubmed ID: 31547367 GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity Endocrinology. 07, 2019 | Pubmed ID: 31099824 Adipocyte-Specific GH Receptor-Null (AdGHRKO) Mice Have Enhanced Insulin Sensitivity With Reduced Liver Triglycerides Endocrinology. 01, 2019 | Pubmed ID: 30462209 MECHANISMS IN ENDOCRINOLOGY: Lessons from Growth Hormone Receptor Gene-disrupted Mice: Are There Benefits of Endocrine Defects? European Journal of Endocrinology. May, 2018 | Pubmed ID: 29459441 Extracellular ATP, As an Energy and Phosphorylating Molecule, Induces Different Types of Drug Resistances in Cancer Cells Through ATP Internalization and Intracellular ATP Level Increase Oncotarget. Oct, 2017 | Pubmed ID: 29152126 Growth Hormone and the Epithelial-to-Mesenchymal Transition The Journal of Clinical Endocrinology and Metabolism. 10, 2017 | Pubmed ID: 28938477 Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms Molecular Cancer Research : MCR. 11, 2016 | Pubmed ID: 27578770 Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice Endocrinology. 05, 2016 | Pubmed ID: 27035649 Salicylketoximes That Target Glucose Transporter 1 Restrict Energy Supply to Lung Cancer Cells ChemMedChem. Nov, 2015 | Pubmed ID: 26332543 The Warburg Effect: Evolving Interpretations of an Established Concept Free Radical Biology & Medicine. Feb, 2015 | Pubmed ID: 25277420 Extracellular ATP is Internalized by Macropinocytosis and Induces Intracellular ATP Increase and Drug Resistance in Cancer Cells Cancer Letters. Sep, 2014 | Pubmed ID: 24973521 Biological and Biomedical Functions of Penta-O-galloyl-D-glucose and Its Derivatives Journal of Natural Medicines. Jul, 2014 | Pubmed ID: 24532420 Constituents of an Extract of Cryptocarya Rubra Housed in a Repository with Cytotoxic and Glucose Transport Inhibitory Effects Journal of Natural Products. Mar, 2014 | Pubmed ID: 24344605 Orally Efficacious Novel Small Molecule 6-chloro-6-deoxy-1,2,3,4-tetra-O-galloyl-α-D-glucopyranose Selectively and Potently Stimulates Insulin Receptor and Alleviates Diabetes Journal of Molecular Endocrinology. 2013 | Pubmed ID: 23549408 A Small-molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-cycle Arrest, and Inhibits Cancer Cell Growth in Vitro and in Vivo Molecular Cancer Therapeutics. Aug, 2012 | Pubmed ID: 22689530 Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice Corinne M. Nielsen*1,2,3, Yanrong Qian*4, Subhodip Adhicary1,5, Yunsheng Li4, Pratik Shriwas1,2,4, Xuan Wang1,2,4, Lindsey Bachmann6, Xiaozhuo Chen1,2,4,7 1Department of Biological Sciences, Ohio University, 2Molecular and Cellular Biology Program, Ohio University, 3Neuroscience Program, Ohio University, 4Edison Biotechnology Institute, Ohio University, 5Translational Biomedical Sciences Program, Ohio University, 6Honors Tutorial College, Ohio University, 7Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University JoVE 62768 癌症研究
Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice Corinne M. Nielsen*1,2,3, Yanrong Qian*4, Subhodip Adhicary1,5, Yunsheng Li4, Pratik Shriwas1,2,4, Xuan Wang1,2,4, Lindsey Bachmann6, Xiaozhuo Chen1,2,4,7 1Department of Biological Sciences, Ohio University, 2Molecular and Cellular Biology Program, Ohio University, 3Neuroscience Program, Ohio University, 4Edison Biotechnology Institute, Ohio University, 5Translational Biomedical Sciences Program, Ohio University, 6Honors Tutorial College, Ohio University, 7Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University JoVE 62768 癌症研究