Irma Joosten Laboratory of Medical Immunology, Department of Laboratory Medicine Radboud University Medical Centre Biography Publications Institution JoVE Articles Irma Joosten has not added a biography. If you are Irma Joosten and would like to personalize this page please email our Author Liaison for assistance. Publications Platelet-derived Microparticles Inhibit IL-17 Production by Regulatory T Cells Through P-selectin Blood. Feb, 2016 | Pubmed ID: 26903549 The Role of Interleukin-1 Beta in the Pathophysiology of Schnitzler's Syndrome Arthritis Research & Therapy. 2015 | Pubmed ID: 26198339 Quantitative Measurement of Immunoglobulins and Free Light Chains Using Mass Spectrometry Analytical Chemistry. Aug, 2015 | Pubmed ID: 26168337 Low-affinity TCR Engagement Drives IL-2-dependent Post-thymic Maintenance of Naive CD4+ T Cells in Aged Humans Aging Cell. Oct, 2015 | Pubmed ID: 26010129 Prominent HLA-G Expression in Liver Disease But Not After Liver Transplantation Transplantation. Dec, 2015 | Pubmed ID: 25961490 Cytokine Release After Treatment With Rituximab in Renal Transplant Recipients Transplantation. Sep, 2015 | Pubmed ID: 25675201 Soluble CD30 Does Not Predict Late Acute Rejection or Safe Tapering of Immunosuppression in Renal Transplantation Transplant Immunology. Jan, 2015 | Pubmed ID: 25446808 KIR and Human Leukocyte Antigen Genotype Associated Risk of Cytomegalovirus Disease in Renal Transplant Patients Transplantation. Jul, 2015 | Pubmed ID: 25427165 Balance of Treg Versus T-effector Cells During Systemic Treatment with Adalimumab and Topical Treatment with Calcipotriol-betamethasone Dipropionate Ointment Experimental Dermatology. Jan, 2015 | Pubmed ID: 25355140 The Number of CCR5 Expressing CD4+ T Lymphocytes is Lower in HIV-infected Long-term Non-progressors with Viral Control Compared to Normal Progressors: a Cross-sectional Study BMC Infectious Diseases. 2014 | Pubmed ID: 25495598 Longitudinal Analysis of T and B Cell Phenotype and Function in Renal Transplant Recipients with or Without Rituximab Induction Therapy PloS One. 2014 | Pubmed ID: 25393622 The Interplay Between Antiviral Immunity and Allo-immune Reactivity After Renal Transplantation: Consortium Between the Centres Amsterdam, Leiden and Nijmegen (ALLOVIR) Transplant Immunology. Oct, 2014 | Pubmed ID: 25239648 Redefining Strategies to Introduce Tolerance-Inducing Cellular Therapy in Human Beings to Combat Autoimmunity and Transplantation Reactions Frontiers in Immunology. 2014 | Pubmed ID: 25177323 Cellular Sources of IL-17 in Psoriasis: a Paradigm Shift? Experimental Dermatology. Nov, 2014 | Pubmed ID: 25039885 Immune Responses to Stress in Rheumatoid Arthritis and Psoriasis Rheumatology (Oxford, England). Oct, 2014 | Pubmed ID: 24850878 The Impact of Exercise on the Variation of Serum Free Light Chains Clinical Chemistry and Laboratory Medicine. Nov, 2014 | Pubmed ID: 24803612 In Vivo Induction of Cutaneous Inflammation Results in the Accumulation of Extracellular Trap-forming Neutrophils Expressing RORγt and IL-17 The Journal of Investigative Dermatology. May, 2014 | Pubmed ID: 24317395 Selective Expansion of Human Natural Killer Cells Leads to Enhanced Alloreactivity Cellular & Molecular Immunology. Mar, 2014 | Pubmed ID: 24240123 Targeting PKC in Human T Cells Using Sotrastaurin (AEB071) Preserves Regulatory T Cells and Prevents IL-17 Production The Journal of Investigative Dermatology. Apr, 2014 | Pubmed ID: 24192715 Crosstalk Between Keratinocytes and T Cells in a 3D Microenvironment: a Model to Study Inflammatory Skin Diseases The Journal of Investigative Dermatology. Mar, 2014 | Pubmed ID: 24121402 Phosphatidylserine Exposure on Stored Red Blood Cells As a Parameter for Donor-dependent Variation in Product Quality Blood Transfusion = Trasfusione Del Sangue. Apr, 2014 | Pubmed ID: 24120596 Immune Responses to Stress After Stress Management Training in Patients with Rheumatoid Arthritis Arthritis Research & Therapy. 2013 | Pubmed ID: 24274618 Gateway to Understanding Microparticles: Standardized Isolation and Identification of Plasma Membrane-derived Vesicles Nanomedicine (London, England). Oct, 2013 | Pubmed ID: 24074388 Human Secondary Lymphoid Organs Typically Contain Polyclonally-activated Proliferating Regulatory T Cells Blood. Sep, 2013 | Pubmed ID: 23950176 The Effects of in Vivo B-cell Depleting Therapy on Ex-vivo Cytokine Production Transplant Immunology. Jun, 2013 | Pubmed ID: 23651756 Iron Status and Systemic Inflammation, but Not Gut Inflammation, Strongly Predict Gender-specific Concentrations of Serum Hepcidin in Infants in Rural Kenya PloS One. 2013 | Pubmed ID: 23460869 Coal Tar Induces AHR-dependent Skin Barrier Repair in Atopic Dermatitis The Journal of Clinical Investigation. Feb, 2013 | Pubmed ID: 23348739 CD19 is a Useful B Cell Marker After Treatment with Rituximab: Comment on the Article by Jones Et Al Arthritis and Rheumatism. Apr, 2013 | Pubmed ID: 23335076 Co-culture of Healthy Human Keratinocytes and T-cells Promotes Keratinocyte Chemokine Production and RORγt-positive IL-17 Producing T-cell Populations Journal of Dermatological Science. Jan, 2013 | Pubmed ID: 23127421 High-dose Vitamin D3 Supplementation is a Requisite for Modulation of Skin-homing Markers on Regulatory T Cells in HIV-infected Patients AIDS Research and Human Retroviruses. Feb, 2013 | Pubmed ID: 22720723 Humanized Mouse Model of Skin Inflammation is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells PloS One. 2012 | Pubmed ID: 23094018 Storage-induced Changes in Erythrocyte Membrane Proteins Promote Recognition by Autoantibodies PloS One. 2012 | Pubmed ID: 22879923 Humoral Anti-KLH Responses in Cancer Patients Treated with Dendritic Cell-based Immunotherapy Are Dictated by Different Vaccination Parameters Cancer Immunology, Immunotherapy : CII. Nov, 2012 | Pubmed ID: 22527252 Rho Kinase Inhibitor Y-27632 Prolongs the Life Span of Adult Human Keratinocytes, Enhances Skin Equivalent Development, and Facilitates Lentiviral Transduction Tissue Engineering. Part A. Sep, 2012 | Pubmed ID: 22519508 Molecular Pathway Profiling of T Lymphocyte Signal Transduction Pathways; Th1 and Th2 Genomic Fingerprints Are Defined by TCR and CD28-mediated Signaling BMC Immunology. 2012 | Pubmed ID: 22413885 Defining Early Human NK Cell Developmental Stages in Primary and Secondary Lymphoid Tissues PloS One. 2012 | Pubmed ID: 22319595 Translating the Role of Vitamin D3 in Infectious Diseases Critical Reviews in Microbiology. May, 2012 | Pubmed ID: 22304022 Seasonal Variation in Vitamin D₃ Levels is Paralleled by Changes in the Peripheral Blood Human T Cell Compartment PloS One. 2012 | Pubmed ID: 22235276 Koebner Phenomenon in Psoriasis is Not Associated with Deletion of Late Cornified Envelope Genes LCE3B and LCE3C The Journal of Investigative Dermatology. Feb, 2012 | Pubmed ID: 22048733 Analyzing the Homeostasis of Signaling Proteins by a Combination of Western Blot and Fluorescence Correlation Spectroscopy Biophysical Journal. Dec, 2011 | Pubmed ID: 22261070 1,25-Dihydroxyvitamin D3 Inhibits Proliferation but Not the Suppressive Function of Regulatory T Cells in the Absence of Antigen-presenting Cells Immunology. Dec, 2011 | Pubmed ID: 22044285 Donor and Recipient HLA/KIR Genotypes Do Not Predict Liver Transplantation Outcome Transplant International : Official Journal of the European Society for Organ Transplantation. Sep, 2011 | Pubmed ID: 21672051 Foxp3+ Regulatory T Cells of Psoriasis Patients Easily Differentiate into IL-17A-producing Cells and Are Found in Lesional Skin The Journal of Investigative Dermatology. Sep, 2011 | Pubmed ID: 21654831 Vitamin D(3) Down-regulates Proinflammatory Cytokine Response to Mycobacterium Tuberculosis Through Pattern Recognition Receptors While Inducing Protective Cathelicidin Production Cytokine. Aug, 2011 | Pubmed ID: 21592820 Anaphylaxis from Passive Transfer of Peanut Allergen in a Blood Product The New England Journal of Medicine. May, 2011 | Pubmed ID: 21591965 1,25-dihydroxyvitamin D3 Modulates Cytokine Production Induced by Candida Albicans: Impact of Seasonal Variation of Immune Responses The Journal of Infectious Diseases. Jan, 2011 | Pubmed ID: 21148505 Liver Grafts Contain a Unique Subset of Natural Killer Cells That Are Transferred into the Recipient After Liver Transplantation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Jul, 2010 | Pubmed ID: 20583081 DNA-PKcs Controls an Endosomal Signaling Pathway for a Proinflammatory Response by Natural Killer Cells Science Signaling. 2010 | Pubmed ID: 20179272 High Log-scale Expansion of Functional Human Natural Killer Cells from Umbilical Cord Blood CD34-positive Cells for Adoptive Cancer Immunotherapy PloS One. 2010 | Pubmed ID: 20169160 Immunotherapy with Regulatory T Cells in Transplantation Immunotherapy. Sep, 2009 | Pubmed ID: 20636028 The Inhibitory Fc Gamma IIb Receptor Dampens TLR4-mediated Immune Responses and is Selectively Up-regulated on Dendritic Cells from Rheumatoid Arthritis Patients with Quiescent Disease Journal of Immunology (Baltimore, Md. : 1950). Oct, 2009 | Pubmed ID: 19734236 The Macrophage Mannose Receptor Induces IL-17 in Response to Candida Albicans Cell Host & Microbe. Apr, 2009 | Pubmed ID: 19380112 Limited Amounts of Dendritic Cells Migrate into the T-cell Area of Lymph Nodes but Have High Immune Activating Potential in Melanoma Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2009 | Pubmed ID: 19318472 Deletion of the Late Cornified Envelope LCE3B and LCE3C Genes As a Susceptibility Factor for Psoriasis Nature Genetics. Feb, 2009 | Pubmed ID: 19169253 Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127 Depletion, Treg Expansion, and Treg Cryopreservation PloS One. 2008 | Pubmed ID: 18776930 Immunological Monitoring of Renal Transplant Recipients to Predict Acute Allograft Rejection Following the Discontinuation of Tacrolimus PloS One. 2008 | Pubmed ID: 18628993 Human CD25highFoxp3pos Regulatory T Cells Differentiate into IL-17-producing Cells Blood. Sep, 2008 | Pubmed ID: 18617638 KIR2DS5 is Associated with Leukemia Free Survival After HLA Identical Stem Cell Transplantation in Chronic Myeloid Leukemia Patients Molecular Immunology. Aug, 2008 | Pubmed ID: 18555529 Ex Vivo Generation of Human Alloantigen-specific Regulatory T Cells from CD4(pos)CD25(high) T Cells for Immunotherapy PloS One. 2008 | Pubmed ID: 18493605 A Novel (Leu183Pro-)mutation in the HFE-gene Co-inherited with the Cys282Tyr Mutation in Two Unrelated Dutch Hemochromatosis Patients Blood Cells, Molecules & Diseases. May-Jun, 2008 | Pubmed ID: 18042412 The Presence of Donor-specific Human Leukocyte Antigen Antibodies Does Not Preclude Successful Withdrawal of Tacrolimus in Stable Renal Transplant Recipients Transplantation. Nov, 2007 | Pubmed ID: 17998862 KIR Gene and KIR Ligand Analysis to Predict Graft Rejection After Renal Transplantation Transplantation. Oct, 2007 | Pubmed ID: 17989611 Allogeneic Stimulation of Naturally Occurring CD4+CD25+ T Cells Induces Strong Regulatory Capacity with Increased Donor-reactivity Transplant Immunology. Jun, 2007 | Pubmed ID: 17493525 The Immunosuppressive Drug FK778 Induces Regulatory Activity in Stimulated Human CD4+ CD25- T Cells Blood. Jan, 2007 | Pubmed ID: 16902146 Antigen-specific Regulatory T-cell Subsets in Transplantation Tolerance Regulatory T-cell Subset Quality Reduces the Need for Quantity Human Immunology. Sep, 2006 | Pubmed ID: 17002896 Ex Vivo Expansion of Human CD4+ CD25high Regulatory T Cells from Transplant Recipients Permits Functional Analysis of Small Blood Samples Journal of Immunological Methods. Jul, 2006 | Pubmed ID: 16860335 CTLA-4 Engagement and Regulatory CD4+CD25+ T Cells Independently Control CD8+-mediated Responses Under Costimulation Blockade Journal of Immunology (Baltimore, Md. : 1950). May, 2006 | Pubmed ID: 16621989 Activation of NK Cells by an Endocytosed Receptor for Soluble HLA-G PLoS Biology. Jan, 2006 | Pubmed ID: 16366734 Rapamycin, and Not Cyclosporin A, Preserves the Highly Suppressive CD27+ Subset of Human CD4+CD25+ Regulatory T Cells Blood. Feb, 2006 | Pubmed ID: 16210336 Cyclosporine Preserves the Anergic State of Human T Cells Induced by Costimulation Blockade in Vitro Transplantation. Aug, 2005 | Pubmed ID: 16123728 CD27/CFSE-based Ex Vivo Selection of Highly Suppressive Alloantigen-specific Human Regulatory T Cells Journal of Immunology (Baltimore, Md. : 1950). Jun, 2005 | Pubmed ID: 15944257 Tolerizing Effects of Co-stimulation Blockade Rest on Functional Dominance of CD4+CD25+ Regulatory T Cells Transplantation. Jan, 2005 | Pubmed ID: 15665762 A Novel Bispecific Antihuman CD40/CD86 Fusion Protein with T-cell Tolerizing Potential Transplantation. Nov, 2004 | Pubmed ID: 15599306 Shift in Expression of HLA-G MRNA Spliceforms in Pregnancies Complicated by Preeclampsia Journal of the Society for Gynecologic Investigation. May, 2004 | Pubmed ID: 15120695 IL-15 and Cognate Antigen Successfully Expand De Novo-induced Human Antigen-specific Regulatory CD4+ T Cells That Require Antigen-specific Activation for Suppression Journal of Immunology (Baltimore, Md. : 1950). Dec, 2003 | Pubmed ID: 14662842 The Proportion of Follicular Fluid CD16+CD56DIM NK Cells is Increased in IVF Patients with Idiopathic Infertility Journal of Reproductive Immunology. Oct, 2003 | Pubmed ID: 14568679 Superior T-cell Suppression by Rapamycin and FK506 over Rapamycin and Cyclosporine A Because of Abrogated Cytotoxic T-lymphocyte Induction, Impaired Memory Responses, and Persistent Apoptosis Transplantation. May, 2003 | Pubmed ID: 12792519 Altered Phenotype of HLA-G Expressing Trophoblast and Decidual Natural Killer Cells in Pathological Pregnancies Human Reproduction (Oxford, England). Apr, 2002 | Pubmed ID: 11925408 Amniotic Fluid Soluble Human Leukocyte Antigen G is Markedly Decreased in Offspring with Neural Tube Defects Early Human Development. Feb, 2002 | Pubmed ID: 11872314 Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture Xuehui He1, Vivian L. de Oliveira1, Romy Keijsers2, Irma Joosten1, Hans JPN Koenen1 1Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Centre, 2Department of Dermatology, Radboud University Medical Centre JoVE 52564 免疫与感染
Lymphocyte Isolation from Human Skin for Phenotypic Analysis and Ex Vivo Cell Culture Xuehui He1, Vivian L. de Oliveira1, Romy Keijsers2, Irma Joosten1, Hans JPN Koenen1 1Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Centre, 2Department of Dermatology, Radboud University Medical Centre JoVE 52564 免疫与感染