Ate G.J. van der Zee Department of Obstetrics and Gynaecology University Medical Center Groningen Biography Publications Institution JoVE Articles Ate G.J. van der Zee has not added a biography. If you are Ate G.J. van der Zee and would like to personalize this page please email our Author Liaison for assistance. Publications HPV16 E6 RNA Interference Enhances Cisplatin and Death Receptor-mediated Apoptosis in Human Cervical Carcinoma Cells Molecular Pharmacology. Feb, 2012 | Pubmed ID: 22328720 The Role of ATM and 53BP1 As Predictive Markers in Cervical Cancer International Journal of Cancer. Journal International Du Cancer. Feb, 2012 | Pubmed ID: 22323184 ESGO Statement on the Role of CA-125 Measurement in Follow-up of Epithelial Ovarian Cancer International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Jan, 2012 | Pubmed ID: 22193647 The Effect of Chemotherapy on Expression of Folate Receptor-alpha in Ovarian Cancer Cellular Oncology (Dordrecht). Feb, 2012 | Pubmed ID: 21647742 Anticancer Drugs Aimed at E6 and E7 Activity in HPV-positive Cervical Cancer Current Cancer Drug Targets. Oct, 2011 | Pubmed ID: 22165971 Potentiation of a P53-SLP Vaccine by Cyclophosphamide in Ovarian Cancer: A Single-arm Phase II Study International Journal of Cancer. Journal International Du Cancer. Dec, 2011 | Pubmed ID: 22139992 Intraoperative Tumor-specific Fluorescence Imaging in Ovarian Cancer by Folate Receptor-α Targeting: First In-human Results Nature Medicine. Oct, 2011 | Pubmed ID: 21926976 Cell Surface Delivery of TRAIL Strongly Augments the Tumoricidal Activity of T Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2011 | Pubmed ID: 21753155 Serum Tryptophan and Kynurenine Concentrations As Parameters for Indoleamine 2,3-dioxygenase Activity in Patients with Endometrial, Ovarian, and Vulvar Cancer International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Oct, 2011 | Pubmed ID: 21720257 Training in Bowel and Upper Abdominal Surgery in Gynaecological Oncology: European Society of Gynecological Oncology (ESGO) Statement International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Oct, 2011 | Pubmed ID: 21720255 Tumor-infiltrating Cytotoxic T Lymphocytes As Independent Prognostic Factor in Epithelial Ovarian Cancer with Wilms Tumor Protein 1 Overexpression Journal of Immunotherapy (Hagerstown, Md. : 1997). Jul-Aug, 2011 | Pubmed ID: 21654520 Laparoscopic Hysterectomy is Preferred over Laparotomy in Early Endometrial Cancer Patients, However Not Cost Effective in the Very Obese European Journal of Cancer (Oxford, England : 1990). Sep, 2011 | Pubmed ID: 21636268 Intraoperative Imaging in Ovarian Cancer: Fact or Fiction? Molecular Imaging. Aug, 2011 | Pubmed ID: 21521557 Involvement of the TGF-beta and Beta-catenin Pathways in Pelvic Lymph Node Metastasis in Early-stage Cervical Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2011 | Pubmed ID: 21385933 Prognostic Cell Biological Markers in Cervical Cancer Patients Primarily Treated with (chemo)radiation: a Systematic Review International Journal of Radiation Oncology, Biology, Physics. Feb, 2011 | Pubmed ID: 21195874 Loss of SerpinA5 Protein Expression is Associated with Advanced-stage Serous Ovarian Tumors Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Mar, 2011 | Pubmed ID: 21102419 Differentiated Vulvar Intraepithelial Neoplasia is Often Found in Lesions, Previously Diagnosed As Lichen Sclerosus, Which Have Progressed to Vulvar Squamous Cell Carcinoma Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Feb, 2011 | Pubmed ID: 21057461 Intraoperative Multispectral Fluorescence Imaging for the Detection of the Sentinel Lymph Node in Cervical Cancer: a Novel Concept Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Oct, 2011 | Pubmed ID: 20835767 Heterologous Prime-boost Immunizations with a Virosomal and an Alphavirus Replicon Vaccine Molecular Pharmaceutics. Feb, 2011 | Pubmed ID: 20825215 The Epidermal Growth Factor Receptor Pathway in Relation to Pelvic Lymph Node Metastasis and Survival in Early-stage Cervical Cancer Human Pathology. Dec, 2010 | Pubmed ID: 21078436 Implementing an Advanced Laparoscopic Procedure by Monitoring with a Visiting Surgeon Journal of Minimally Invasive Gynecology. Nov-Dec, 2010 | Pubmed ID: 20955987 Potential Target Antigens for a Universal Vaccine in Epithelial Ovarian Cancer Clinical & Developmental Immunology. 2010 | Pubmed ID: 20885926 Current Controversies in the Management of Patients with Early-stage Vulvar Cancer Current Opinion in Oncology. Sep, 2010 | Pubmed ID: 20616719 Routine Evaluation and Treatment of Unexplained Menorrhagia: Do We Consider Haemostatic Disorders? European Journal of Obstetrics, Gynecology, and Reproductive Biology. Oct, 2010 | Pubmed ID: 20576344 European Network of Gynaecological Oncological Trial Groups' Requirements for Trials Between Academic Groups and Pharmaceutical Companies International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Apr, 2010 | Pubmed ID: 20375816 Gene Promoter Methylation Patterns Throughout the Process of Cervical Carcinogenesis Cellular Oncology : the Official Journal of the International Society for Cellular Oncology. 2010 | Pubmed ID: 20208141 Update on the Sentinel Lymph Node Procedure in Vulvar Cancer Expert Review of Anticancer Therapy. Jan, 2010 | Pubmed ID: 20014886 The Extrinsic Apoptosis Pathway and Its Prognostic Impact in Ovarian Cancer Gynecologic Oncology. Mar, 2010 | Pubmed ID: 19959214 The Prognostic Role of Classical and Nonclassical MHC Class I Expression in Endometrial Cancer International Journal of Cancer. Journal International Du Cancer. Mar, 2010 | Pubmed ID: 19728333 Multimodality Treatment Warranted for Ovarian Cancer: Immunotherapy, a Prerequisite to Improve Prognosis for This Vicious Disease Immunotherapy. Mar, 2009 | Pubmed ID: 20635935 Expression of Epidermal Growth Factor Receptor (EGFR) and Activated EGFR Predict Poor Response to (chemo)radiation and Survival in Cervical Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2009 | Pubmed ID: 19920104 Methylation Markers for CCNA1 and C13ORF18 Are Strongly Associated with High-grade Cervical Intraepithelial Neoplasia and Cervical Cancer in Cervical Scrapings Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Nov, 2009 | Pubmed ID: 19843677 [New Strategies for Screening Cervical Cancer; Response to the Dutch College of General Practitioner's Practice Guideline 'Prevention and Early Diagnosis of Cervical Cancer'] Nederlands Tijdschrift Voor Geneeskunde. 2009 | Pubmed ID: 19785834 Identification of Candidate Epigenetic Biomarkers for Ovarian Cancer Detection Oncology Reports. Oct, 2009 | Pubmed ID: 19724865 The Prognostic Value of TRAIL and Its Death Receptors in Cervical Cancer International Journal of Radiation Oncology, Biology, Physics. Sep, 2009 | Pubmed ID: 19695437 TP53 Codon 72 Polymorphism and Cervical Cancer: a Pooled Analysis of Individual Data from 49 Studies The Lancet Oncology. Aug, 2009 | Pubmed ID: 19625214 Immunization with a P53 Synthetic Long Peptide Vaccine Induces P53-specific Immune Responses in Ovarian Cancer Patients, a Phase II Trial International Journal of Cancer. Journal International Du Cancer. Nov, 2009 | Pubmed ID: 19621448 The Role of Sentinel Node Biopsy in Gynecological Cancer: a Review Current Opinion in Oncology. Sep, 2009 | Pubmed ID: 19593136 Aromatase, Cyclooxygenase 2, HER-2/neu, and P53 As Prognostic Factors in Endometrioid Endometrial Cancer International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. May, 2009 | Pubmed ID: 19509570 Sentinel Lymph Node Biopsy in Patients with Gynecologic Cancers Expert Panel Statement from the International Sentinel Node Society Meeting, February 21, 2008 Gynecologic Oncology. Aug, 2009 | Pubmed ID: 19457548 Enhanced Antitumor Efficacy of a DR5-specific TRAIL Variant over Recombinant Human TRAIL in a Bioluminescent Ovarian Cancer Xenograft Model Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2009 | Pubmed ID: 19276284 Down-regulation of Proteasomal Subunit MB1 is an Independent Predictor of Improved Survival in Ovarian Cancer Gynecologic Oncology. May, 2009 | Pubmed ID: 19243813 [The Limitations of Observational Research] Nederlands Tijdschrift Voor Geneeskunde. Jan, 2009 | Pubmed ID: 19235351 [Primary Surgery by a Gynecological Oncologist Improves the Prognosis in Patients with Ovarian Carcinoma] Nederlands Tijdschrift Voor Geneeskunde. Jan, 2009 | Pubmed ID: 19198207 Survival-related Profile, Pathways, and Transcription Factors in Ovarian Cancer PLoS Medicine. Feb, 2009 | Pubmed ID: 19192944 Prognostic Significance of Tumor-infiltrating T-lymphocytes in Primary and Metastatic Lesions of Advanced Stage Ovarian Cancer Cancer Immunology, Immunotherapy : CII. Mar, 2009 | Pubmed ID: 18791714 Targeting Pro-apoptotic Trail Receptors Sensitizes HeLa Cervical Cancer Cells to Irradiation-induced Apoptosis International Journal of Radiation Oncology, Biology, Physics. Oct, 2008 | Pubmed ID: 18793956 Survival of Ovarian Cancer Patients Overexpressing the Tumour Antigen P53 is Diminished in Case of MHC Class I Down-regulation Gynecologic Oncology. Sep, 2008 | Pubmed ID: 18571704 A Robust Ex Vivo Model for Evaluation of Induction of Apoptosis by RhTRAIL in Combination with Proteasome Inhibitor MG132 in Human Premalignant Cervical Explants International Journal of Cancer. Journal International Du Cancer. Sep, 2008 | Pubmed ID: 18567003 Genome-wide Promoter Analysis Uncovers Portions of the Cancer Methylome Cancer Research. Apr, 2008 | Pubmed ID: 18413733 The Effect of Pre-existing Immunity on the Capacity of Influenza Virosomes to Induce Cytotoxic T Lymphocyte Activity Vaccine. May, 2008 | Pubmed ID: 18400343 A New Perspective on Transcriptional System Regulation (TSR): Towards TSR Profiling PloS One. 2008 | Pubmed ID: 18297136 Sentinel Node Dissection is Safe in the Treatment of Early-stage Vulvar Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2008 | Pubmed ID: 18281661 Distinguishing Benign and Malignant Pelvic Masses: the Value of Different Diagnostic Methods in Everyday Clinical Practice European Journal of Obstetrics, Gynecology, and Reproductive Biology. Jan, 2008 | Pubmed ID: 17118522 Chip-LC-MS for Label-free Profiling of Human Serum Electrophoresis. Dec, 2007 | Pubmed ID: 18041038 ESGO Statement on Cervical Cancer Vaccination International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Nov-Dec, 2007 | Pubmed ID: 17997794 Combining Multiple Serum Tumor Markers Improves Detection of Stage I Epithelial Ovarian Cancer Gynecologic Oncology. Dec, 2007 | Pubmed ID: 17920110 Multiple Testing Issues in Discriminating Compound-related Peaks and Chromatograms from High Frequency Noise, Spikes and Solvent-based Noise in LC-MS Data Sets Statistical Applications in Genetics and Molecular Biology. 2007 | Pubmed ID: 17910529 Evidence Based Selection of Housekeeping Genes PloS One. 2007 | Pubmed ID: 17878933 Profiling Studies in Ovarian Cancer: a Review The Oncologist. Aug, 2007 | Pubmed ID: 17766655 Beware of Amenorrhea During Tamoxifen: It May Be a Wolf in Sheep's Clothing Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2007 | Pubmed ID: 17704431 Serum Cytokine Profiling As a Diagnostic and Prognostic Tool in Ovarian Cancer: a Potential Role for Interleukin 7 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2007 | Pubmed ID: 17438097 Sulindac Treatment in Hereditary Non-polyposis Colorectal Cancer European Journal of Cancer (Oxford, England : 1990). May, 2007 | Pubmed ID: 17434727 An Overview of Innovative Techniques to Improve Cervical Cancer Screening Cellular Oncology : the Official Journal of the International Society for Cellular Oncology. 2006 | Pubmed ID: 17167177 A Biological Question and a Balanced (orthogonal) Design: the Ingredients to Efficiently Analyze Two-color Microarrays with Confirmatory Factor Analysis BMC Genomics. 2006 | Pubmed ID: 16968534 Gynecologic Examination and Cervical Biopsies After (chemo) Radiation for Cervical Cancer to Identify Patients Eligible for Salvage Surgery International Journal of Radiation Oncology, Biology, Physics. Nov, 2006 | Pubmed ID: 16904839 Assessment of Gene Promoter Hypermethylation for Detection of Cervical Neoplasia International Journal of Cancer. Journal International Du Cancer. Oct, 2006 | Pubmed ID: 16736496 Patterns and Frequency of Recurrences of Squamous Cell Carcinoma of the Vulva Gynecologic Oncology. Oct, 2006 | Pubmed ID: 16631238 Surgery by Consultant Gynecologic Oncologists Improves Survival in Patients with Ovarian Carcinoma Cancer. Feb, 2006 | Pubmed ID: 16369985 Proteasome Inhibitor MG132 Sensitizes HPV-positive Human Cervical Cancer Cells to RhTRAIL-induced Apoptosis International Journal of Cancer. Journal International Du Cancer. Apr, 2006 | Pubmed ID: 16287099 Distinct Regulation and Impact of Type 1 T-cell Immunity Against HPV16 L1, E2 and E6 Antigens During HPV16-induced Cervical Infection and Neoplasia International Journal of Cancer. Journal International Du Cancer. Feb, 2006 | Pubmed ID: 16108057 Clinical Potential of Inhibitors of Survival Pathways and Activators of Apoptotic Pathways in Treatment of Cervical Cancer: Changing the Apoptotic Balance The Lancet Oncology. Aug, 2005 | Pubmed ID: 16054570 Sensitivity to Fas-mediated Apoptosis in High-risk HPV-positive Human Cervical Cancer Cells: Relationship with Fas, Caspase-8, and Bid Gynecologic Oncology. May, 2005 | Pubmed ID: 15863130 Preoperative Serum Squamous Cell Carcinoma Antigen Levels in Clinical Decision Making for Patients with Early-stage Cervical Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2005 | Pubmed ID: 15735121 Lymphvascular Space Involvement: an Independent Prognostic Factor in Endometrial Cancer Gynecologic Oncology. Mar, 2005 | Pubmed ID: 15721428 HLA Genes and Other Candidate Genes Involved in Susceptibility for (pre)neoplastic Cervical Disease International Journal of Oncology. Mar, 2005 | Pubmed ID: 15703836 Fas and Fas Ligand in Cyst Fluids, Serum and Tumors of Patients with Benign and (borderline) Malignant Ovarian Tumors International Journal of Oncology. Feb, 2005 | Pubmed ID: 15645122 Methylenetetrahydrofolate Reductase (MTHFR) and Susceptibility for (pre)neoplastic Cervical Disease Human Genetics. Mar, 2005 | Pubmed ID: 15635481 Preoperative Sensitivity and Specificity for Early-stage Ovarian Cancer when Combining Cancer Antigen CA-125II, CA 15-3, CA 72-4, and Macrophage Colony-stimulating Factor Using Mixtures of Multivariate Normal Distributions Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2004 | Pubmed ID: 15381683 Three Biomarkers Identified from Serum Proteomic Analysis for the Detection of Early Stage Ovarian Cancer Cancer Research. Aug, 2004 | Pubmed ID: 15313933 Detecting Cervical Cancer by Quantitative Promoter Hypermethylation Assay on Cervical Scrapings: a Feasibility Study Molecular Cancer Research : MCR. May, 2004 | Pubmed ID: 15192122 Modern Management of Vulvar Cancer Current Opinion in Obstetrics & Gynecology. Feb, 2004 | Pubmed ID: 15128010 Letter Commenting on "Patholologic Finding in Prophylactic Oophorectomy Specimens in High-risk Women" (87:52-6) by Pamela Paley, Et Al. (, Fax: +31-206-685-9607) Gynecologic Oncology. May, 2004 | Pubmed ID: 15099985 Elevated HTERT MRNA Levels: A Potential Determinant of Bronchial Squamous Cell Carcinoma (in Situ) International Journal of Cancer. Journal International Du Cancer. Apr, 2004 | Pubmed ID: 14961580 The Value of Routine Follow-up in Patients Treated for Carcinoma of the Vulva Cancer. Dec, 2003 | Pubmed ID: 14669281 Toward New Strategies to Select Young Endometrial Cancer Patients for Mismatch Repair Gene Mutation Analysis Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2003 | Pubmed ID: 14645426 Telomerase in Relation to Expression of P53, C-Myc and Estrogen Receptor in Ovarian Tumours International Journal of Oncology. Nov, 2003 | Pubmed ID: 14532990 Gynecologic Screening in Hereditary Nonpolyposis Colorectal Cancer Gynecologic Oncology. Oct, 2003 | Pubmed ID: 14529665 Re: Further Data on the Usefulness of Sentinel Lymph Node Identification and Ultrastaging in Vulvar Squamous Cell Carcinoma. Gynecol Oncol. 2003 Jan;88(1):29-34 Gynecologic Oncology. Sep, 2003 | Pubmed ID: 14515864 HLA Class I Alleles and Cervical Neoplasia The Journal of Infectious Diseases. May, 2003 | Pubmed ID: 12721951 Human Kallikrein 6 (hK6): a New Potential Serum Biomarker for Diagnosis and Prognosis of Ovarian Carcinoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2003 | Pubmed ID: 12637468 The Serum Concentration of Human Kallikrein 10 Represents a Novel Biomarker for Ovarian Cancer Diagnosis and Prognosis Cancer Research. Feb, 2003 | Pubmed ID: 12591730 Sentinel Node Techniques in Cancer of the Vulva Current Women's Health Reports. Feb, 2003 | Pubmed ID: 12521546 Vulvar Carcinoma. The Price of Less Radical Surgery Cancer. Dec, 2002 | Pubmed ID: 12436439 Vulvar Melanoma: is There a Role for Sentinel Lymph Node Biopsy? Cancer. Jan, 2002 | Pubmed ID: 11905414 Molecular and Clinical Characteristics of MSH6 Variants: an Analysis of 25 Index Carriers of a Germline Variant American Journal of Human Genetics. Jan, 2002 | Pubmed ID: 11709755 Telomerase Targeting in Cancer Treatment: New Developments Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. Apr, 1999 | Pubmed ID: 11504478 Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology Lucia M.A. Crane1, George Themelis2, K. Tim Buddingh1, Niels J. Harlaar1, Rick G. Pleijhuis1, Athanasios Sarantopoulos2, Ate G.J. van der Zee3, Vasilis Ntziachristos2, Gooitzen M. van Dam1 1Department of Surgery, Division of Surgical Oncology, University Medical Center Groningen, 2Helmholtz Zentrum, Technical University Munich, 3Department of Obstetrics and Gynaecology, University Medical Center Groningen JoVE 2225 医学
Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology Lucia M.A. Crane1, George Themelis2, K. Tim Buddingh1, Niels J. Harlaar1, Rick G. Pleijhuis1, Athanasios Sarantopoulos2, Ate G.J. van der Zee3, Vasilis Ntziachristos2, Gooitzen M. van Dam1 1Department of Surgery, Division of Surgical Oncology, University Medical Center Groningen, 2Helmholtz Zentrum, Technical University Munich, 3Department of Obstetrics and Gynaecology, University Medical Center Groningen JoVE 2225 医学