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Journal
Biochemistry
Imaging the Motion of Fully Reconstituted Cdc45/Mcm2-7/GINS (CMG)
Imaging the Motion of Fully Reconstituted Cdc45/Mcm2-7/GINS (CMG)
July 26, 2024
杂交集合和单分子检测对完全重构的 CMG 的运动进行成像
00:00 min
•
128 Views
Daniel Ramírez Montero
1
,
Humberto Sánchez
1
,
Edo van Veen
1
,
Theo van Laar
1
,
Belén Solano
1
,
John F. X. Diffley
2
,
Nynke H. Dekker
1,3
1
Department of Bionanoscience, Kavli Institute of Nanoscience
,
Delft University of Technology
,
2
Chromosome Replication Laboratory
,
Francis Crick Institute
,
3
Department of Physics and Kavli Institute of Nanoscience Discovery
,
University of Oxford
Summary
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Automatically Generated
我们报道了一种杂交集成和单分子测定法，用于直接成像和量化荧光标记、完全重组的 Cdc45/Mcm2-7/GINS （CMG） 解旋酶在光阱中固定的线性 DNA 分子上的运动。
Article
