1Center for Bionics and Pain Research, 2Center for Advanced Reconstruction of Extremities,Sahlgrenska University Hospital, 3Department of Electrical Engineering,Chalmers University of Technology, 4Bionics Institute, 5IV Clinica Ortoplastica,IRCCS Istituto Ortopedico Rizzoli, 6Department of Hand Surgery, Institute of Clinical Sciences, Sahlgrenska Academy,University of Gothenburg, Sahlgrenska University Hospital, 7Department of Orthopedic, Hand Unit,Worker Hospital, 8College of Medicine and Veterinary Medicine, The Queen’s Medical Research Institute,The University of Edinburgh, 9Canniesburn Plastic Surgery Unit,Glasgow Royal Infirmary, 10College of Medicine, Veterinary & Life Sciences,The University of Glasgow, 11Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry,University of Alberta, 12Plastics and Reconstructive Surgery, Dandenong Hospital,Monash Health, 13Division of Plastic and Reconstructive Surgery,Massachusetts General Hospital &, Harvard Medical School, 14Section of Plastic Surgery, Department of Surgery,Michigan Medicine, 15Department of Surgery,Uniformed Services University of the Health Sciences and Walter Reed National Military Medical Center, 16Department of Plastic and Reconstructive Surgery,Ohio State University, 17Clinical Laboratory for Bionic Extremity Reconstruction, Department of Plastic, Reconstructive and Aesthetic Surgery,Medical University Vienna, 18Division of Plastic Surgery, Department of Surgery,Northwestern Feinberg School of Medicine, 19Medical Bionics Department,University of Melbourne, 20Prometei Pain Rehabilitation Center
Il protocollo delinea la procedura chirurgica per il trattamento del dolore post-amputazione mediante Reinnervazione Muscolare Mirata (TMR). La TMR sarà confrontata con altre due tecniche chirurgiche, in particolare l’interfaccia rigenerativa del nervo periferico (RPNI) e l’escissione del neuroma, seguita da un immediato seppellimento all’interno del muscolo nel contesto di uno studio internazionale randomizzato controllato.
