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January 13, 2023
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1Institute of Clinical Medicine, Faculty of Medicine,University of Oslo, 2Department of Neonatal Intensive Care, Division of Pediatric and Adolescent Medicine,Oslo University Hospital Rikshospitalet, 3Department of Pediatric Research, Division of Paediatric and Adolescent Medicine,Oslo University Hospital Rikshospitalet, 4Department of Pediatrics,Vestfold Hospital Trust, 5Department of Anesthesiology,Oslo University Hospital Rikshospitalet, 6Department of Pediatrics, Faculty of Medicine and Dentistry,University of Alberta, 7Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit,Royal Alexandra Hospital, 8Division of Paediatric and Adolescent Medicine, Institute of Clinical Medicine,University of Oslo, 9Department of Paediatrics and Adolescent Health,University of Botswana, 10Department of Pediatric Research, Oslo University Hospital,University of Oslo, 11Department of Pediatrics, Robert H Lurie Medical Research Center,Northwestern University Chicago
Summary
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この子豚モデルは、手術器具、心停止までの窒息、蘇生、および蘇生後の観察を含む。このモデルは、動物ごとに複数回サンプリングすることを可能にし、継続的な侵襲的動脈血圧、ECG、および非侵襲的心拍出量モニタリングを使用することにより、周産期仮死および新生児心肺蘇生法における血行動態および心臓病態生理に関する知識を提供します。
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Keyword Extraction:Piglet Perinatal Asphyxia ModelCardiac InjuryHemodynamicsCardiac ArrestResuscitationReturn Of Spontaneous CirculationNeonatal Cardiopulmonary ResuscitationPulseless Electrical ActivitySurgical InterventionInternal Jugular VeinCentral Venous CatheterFentanyl IVBalanced Carbohydrate Electrolyte Solution
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Cite this Article
Stenersen, E. O., Olsen, A., Melheim, M., Solberg, R., Dannevig, I., Schmölzer, G., Cheung, P., Nakstad, B., Saugstad, O. D., Rønnestad, A., Solevåg, A. L. A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation. J. Vis. Exp. (191), e64788, doi:10.3791/64788 (2023).
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