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Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization
JoVE Journal
Biochemistry
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JoVE Journal Biochemistry
Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization

Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization

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3,153 Views

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08:27 min

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July 27, 2021

DOI:

10.3791/62732-v

DOI:
10.3791/62732-v

•

08:27 min
July 27, 2021

•

78 Views
, ,
1Max-Planck-Institute of Molecular Plant Physiology, 2Center of Plant Systems Biology and Biotechnology

Summary

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In this protocol, we present an optimized workflow, which combines an efficient and fast sample preparation of many samples. In addition, we provide a step-by-step guide to reduce analytical variations for high-throughput evaluation of metabolic GWAS studies.

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Bulut, M., Fernie, A. R., Alseekh, S. Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization. J. Vis. Exp. (173), e62732, doi:10.3791/62732 (2021).

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