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Ultralyd-guidet Ortotopisk implantation af murin Pankreatisk ductal adenocarcinoma
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1Department of Medicine, Perelman School of Medicine,University of Pennsylvania, 2Pancreatic Cancer Mouse Hospital, Perelman School of Medicine,University of Pennsylvania, 3Abramson Cancer Center, Perelman School of Medicine,University of Pennsylvania, 4Parker Institute for Cancer Immunotherapy, Perelman School of Medicine,University of Pennsylvania
Chapters
- 00:04Title
- 01:08Pre-Surgical Preparation
- 02:17Ultrasound-Guided Pancreatic Ductal Adenocarcinoma (PDA) Cell Implantation
- 04:28Results: Representative Ultrasound-Guided Orthotopic Murine Pancreatic Ductal Adenocarcinoma Implantation
- 05:50Conclusion
Vi beskriver en protokol til ultralyd guidet implantation af murine-afledte pancreas duktalt adenocarcinom cellelinjer direkte ind i den indfødte tumor site. Denne fremgangsmåde resulterede i bugspytkirtel tumorer detekterbare ved ultralydsscanning inden for 2-4 ugers injektion, og signifikant reduceret andelen tumor celle såning på peritonealdialyse væggen i forhold til kirurgisk ortotopisk implantation.
