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腫瘍抗原特異的T細胞の生成にヒト誘導多能性幹細胞を用いた
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells
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腫瘍抗原特異的T細胞の生成にヒト誘導多能性幹細胞を用いた

日本語

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9,932 Views

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10:57 min

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October 24, 2019

DOI:

10.3791/59997-v

DOI:
10.3791/59997-v

•

10:57 min
October 24, 2019

•

5 Views
, , , , , ,
1Surgery Branch,National Cancer Institute, NIH, 2Center for Cell-Based Therapy,National Cancer Institute, NIH, 3Laboratory of Immunology, Institute for Frontier Life and Medical Sciences,Kyoto University

Summary

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本稿では、OP9/DLL1共培養系を用いて機能性腫瘍抗原特異的人工多能性幹細胞由来CD8αβ+単陽性T細胞を生成する方法について説明する。

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Cite this Article

Good, M. L., Vizcardo, R., Maeda, T., Tamaoki, N., Malekzadeh, P., Kawamoto, H., Restifo, N. P. Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells. J. Vis. Exp. (152), e59997, doi:10.3791/59997 (2019).

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