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Uso de la Invertebrada Galleria mellonella como Modelo de Infección para Estudiar el Complejo Mycobacterium tuberculosis
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Immunology and Infection
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JoVE Journal Immunology and Infection
Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex
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Uso de la Invertebrada Galleria mellonella como Modelo de Infección para Estudiar el Complejo Mycobacterium tuberculosis

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11,570 Views

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09:23 min

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June 30, 2019

DOI:

10.3791/59703-v

DOI:
10.3791/59703-v

•

09:23 min
June 30, 2019

•

12 Views
, , , , , ,
1Section of Pediatric Infectious Diseases and Allergy, Department of Medicine,Imperial College London, 2Department of Pharmacy,National University of Singapore, 3MRC Centre for Molecular Bacteriology and Infection, Department of Medicine,Imperial College London

Summary

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Galleria mellonella se estableció recientemente como un modelo de infección reproducible, barato y éticamente aceptable para el complejo Mycobacterium tuberculosis. Aquí describimos y demostramos los pasos dados para establecer una infección exitosa de G. mellonella con Bioluminiscente Mycobacterium bovis BCG lux.

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Cite this Article

Asai, M., Li, Y., Khara, J. S., Gladstone, C. A., Robertson, B. D., Langford, P. R., Newton, S. M. Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex. J. Vis. Exp. (148), e59703, doi:10.3791/59703 (2019).

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