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皿に血液脳腫瘍-障壁を使用して生体ペイロード配信で予測
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish
Please note that all translations are automatically generated. Click here for the English version.

皿に血液脳腫瘍-障壁を使用して生体ペイロード配信で予測

日本語

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8,805 Views

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13:34 min

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April 16, 2019

DOI:

10.3791/59384-v

DOI:
10.3791/59384-v

•

13:34 min
April 16, 2019

•

3 Views
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1Research Programs Unit, Translational Cancer Medicine Research Program,University of Helsinki, 2Wihuri Research Institute, Biomedicum Helsinki,University of Helsinki, 3Laboratory Animal Center, Helsinki Institute of Life Science (HiLIFE),University of Helsinki

Summary

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中枢神経系腫瘍にターゲティングは大きな課題です。ここで我々 はマウスやヒトの細胞を用いた血液脳腫瘍関門の in vitro における模倣を生産し、中枢神経系腫瘍生体内ターゲットの予測可能性の重要性を議論するためのプロトコルについて説明します。

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Cite this Article

Le Joncour, V., Karaman, S., Laakkonen, P. M. Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish. J. Vis. Exp. (146), e59384, doi:10.3791/59384 (2019).

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