/
/
Functional Magnetic Resonance Spectroscopy at 7 T in the Rat Barrel Cortex During Whisker Activation
A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:04Title
- 00:43Rat Placement and Whisker Stimulation Confirmation
- 02:37Blood-Oxygen-Level-Dependent Functional Magnetic Resonance Imaging (BOLD fMRI) Acquisition
- 03:39BOLD Processing
- 04:38Proton Magnetic Resonance Spectroscopy (MRS) Acquisitions and Processing
- 07:22Results: Representative fMRS Analysis of Rat Barrel Cortex Responses to Whisker Activation
- 08:57Conclusion
After checking by blood-oxygen-level-dependent functional magnetic resonance imaging (BOLD fMRI) that the corresponding somatosensory barrel field cortex area (called S1BF) is correctly activated, the main goal of this study is to quantify lactate content fluctuations in the activated rat brains by localized proton magnetic resonance spectroscopy (1H-MRS) at 7 T.
Tags
Keywords:
Functional Magnetic Resonance SpectroscopyRat Barrel CortexWhisker ActivationNeurogeneticsMetabolic ChangesIn VivoNon-invasivePathological AnimalsGenetically Modified AnimalsBreathing SensorAir Puff SystemSolenoid Control ValveBlood Oxygen Level Dependent Functional Resonance ImagingT2 Star FID EPI Sequence
