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In Vitro Ensaio para estudar a agregação da proteína Tau e rastreio de drogas
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
In Vitro Assay for Studying the Aggregation of Tau Protein and Drug Screening

In Vitro Ensaio para estudar a agregação da proteína Tau e rastreio de drogas

17,521 Views

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09:49 min

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November 20, 2018

DOI:

10.3791/58570-v

DOI:
10.3791/58570-v

•

09:49 min
November 20, 2018

•

4 Views
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1Janssen Prevention Center,Janssen Pharmaceutical Companies of Johnson and Johnson

Tags

Tau ProteinAlzheimer’s DiseaseTauopathiesAggregation AssayDrug ScreeningNucleation-dependent PolymerizationRecombinant TauFluorescenceSEC-MALSHeparinThioflavin-TMicroplate Reader

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Crespo, R., Koudstaal, W., Apetri, A. In Vitro Assay for Studying the Aggregation of Tau Protein and Drug Screening. J. Vis. Exp. (141), e58570, doi:10.3791/58570 (2018).

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