Journal
/
Chemistry
/
制备和评价<sup>99米</sup>锝标记的三齿螯合物预靶向使用生物正交化学
JoVE Journal
Chemistry
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Chemistry
Preparation and Evaluation of 99mTc-labeled Tridentate Chelates for Pre-targeting Using Bioorthogonal Chemistry
Please note that all translations are automatically generated. Click here for the English version.

制备和评价<sup>99米</sup>锝标记的三齿螯合物预靶向使用生物正交化学

English

Automatically Generated

8,031 Views

•

10:54 min

•

February 04, 2017

DOI:

10.3791/55188-v

DOI:
10.3791/55188-v

•

10:54 min
February 04, 2017

•

4 Views
, , , ,
1Department of Chemistry and Chemical Biology,McMaster University

Summary

Automatically generated

Here, we describe a protocol for radiolabeling and in vivo testing of tridentate 99mTc(I) chelate-tetrazine derivatives for pre-targeting and bioorthogonal chemistry.

Explore More Videos

99mTc-labeled Tridentate ChelatesPre-targetingBioorthogonal ChemistryTetrazinesTechnetium-99mRadiolabelingMicrowave SynthesisTargeting VectorsRadiopharmaceuticalsDiagnostic ImagingRadiotherapy

Read Article

Cite this Article

Bilton, H. A., Ahmad, Z., Janzen, N., Czorny, S., Valliant, J. F. Preparation and Evaluation of 99mTc-labeled Tridentate Chelates for Pre-targeting Using Bioorthogonal Chemistry. J. Vis. Exp. (120), e55188, doi:10.3791/55188 (2017).

Download .ris file

Copy

Share Video

.

Copy