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抗原特异性在体内使用CFSE标记的靶细胞的杀伤含量

JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection

Antigen Specific In Vivo Killing Assay using CFSE Labeled Target Cells

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抗原特异性在体内使用CFSE标记的靶细胞的杀伤含量

19,353 Views

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09:49 min

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November 09, 2010

DOI:

DOI:

•

09:49 min

November 09, 2010

•

8 Views

Marina Durward¹, Jerome Harms², Gary Splitter²

¹Pathology and Laboratory Medicine,University of Wisconsin-Madison, ²Pathobiological Sciences,University of Wisconsin-Madison

Summary

许多感染引起强烈的CTL反应，但偶尔，响应细胞的数量不关联控制病原体<sup> 1</sup>。 CTL的质量的措施之一是他们杀了专门的能力<sup> 2</sup>。 CFSE标签的靶细胞，可用于研究这种CTL反应质量<em>在体内</em<sup> 3,4</sup>。

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