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用于检测按蚊媒介中恶性疟原虫感染的标准膜喂养测定
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İmmünoloji ve Enfeksiyon
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JoVE Journal İmmünoloji ve Enfeksiyon
Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors
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用于检测按蚊媒介中恶性疟原虫感染的标准膜喂养测定

DOI:
10.3791/63546-v

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05:28 min

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May 12, 2022

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, ,
1Wits Research Institute for Malaria, School of Pathology, Faculty of Health Sciences,University of the Witwatersrand, 2Centre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Diseases,National Health Laboratory Service

Bölümler

  • 00:04Introduction
  • 00:49Artificial Infection of Mosquitoes through the SMFA
  • 02:28Preparation and Dissection of Infected Mosquitoes
  • 03:31Results: Identification and Assessment of Potential Antimalarial Compounds
  • 04:28Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

标准膜喂养测定（SMFA）被视为评估和鉴定潜在抗疟化合物的金标准。这种人工喂养系统用于感染蚊子，以进一步评估这些化合物对 恶性疟原 虫寄生虫强度和患病率的影响。

Etiketler

Plasmodium FalciparumAnopheles MosquitoMembrane Feeding AssayMalaria TransmissionGametocyte-infected BloodMosquito InfectionOocyst DetectionMidgut DissectionLaboratory ScreeningTransmission-blocking Compounds

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