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Transuterine foetale tracheale occlusie model in muizen
1The Center for Fetal, Cellular & Molecular Therapy, Cincinnati Fetal Center, Division of Pediatric General and Thoracic Surgery,Cincinnati Children’s Hospital Medical Center, 2Department of Pediatric Surgery,Tekirdag Namik Kemal University School of Medicine, 3The Division of Critical Care Medicine, Department of Pediatrics,Cincinnati Children’s Hospital Medical Center
Bölümler
- 00:04Introduction
- 00:45Preparation
- 01:37Laparotomy
- 02:12Tracheal Occlusion
- 03:47Harvest
- 04:13Histology and Tissue Processing for Protein and DNA Analyses
- 05:06Results: Histological Analyses of the Fetal Lung Tissue Dissected Post TO
- 05:54Conclusion
Verschillende diermodellen van congenitale diafragmatische hernia en foetale tracheale occlusie bieden voor- en nadelen met betrekking tot ethische kwesties, kosten, chirurgische moeilijkheidsgraad, grootte, overlevingspercentages en beschikbaarheid van genetische hulpmiddelen. Dit model biedt een nieuw hulpmiddel om de impact van zowel tracheale occlusie als verhoogde luminale druk op de longontwikkeling te bestuderen.
