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Organóides neurais humanos para estudar câncer cerebral e doenças neurodegenerativas
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Organóides neurais humanos para estudar câncer cerebral e doenças neurodegenerativas
1Laboratory of Tumor Immunology, Translational Research Center in Onco-Hematology, Department of Internal Medicine Specialties, Faculty of Medicine,University of Geneva, 2Department of Pathology and Immunology, University Medical Center,University of Geneva, 3Laboratory of Toxicology and Therapeutic Drug Monitoring,Geneva University Hospitals, 4Tissue Engineering Laboratory, Hepia/HES-SO,University of Applied Sciences Western Switzerland, 5Laboratory of Experimental cell therapy, Department of Diagnostics,Geneva University Hospitals
Bölümler
- 00:04Başlık
- 00:52hESC-derived Neural Organoids for Glioblastoma Multiforme Studies
- 04:39hESC-derived Dopaminergic Organoids for Parkinson s Disease Studies
- 08:12Results: Generation of Dopaminergic Neural Organoid and Electrophysiological and Morphological Analysis
- 09:14Conclusion
Este estudo introduz e descreve protocolos para derivar dois organóides neurais humanos específicos como um modelo relevante e exato para estudar 1) desenvolvimento humano do glioblastoma dentro dos organóides neural humanos exclusivamente nos seres humanos e 2) neurônio dopaminérgicos diferenciação, gerando um organoide tridimensional.
