This manuscript describes the use of transgenic reporter mice and different administration routes of fluorescent dyes in angiotensin II-induced hypertension using intravital video microscopy of blood vessels to evaluate the activation of immune cells and their ability to roll and adhere to the endothelium.
Lagrange, J., Kossmann, S., Kiouptsi, K., Wenzel, P. Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice: Techniques and Pitfalls. J. Vis. Exp. (131), e56948, doi:10.3791/56948 (2018).