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성인 쥐의 Subpial Adeno-associated Virus 9 (AAV9) 벡터 전달
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Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice
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성인 쥐의 Subpial Adeno-associated Virus 9 (AAV9) 벡터 전달

16,934 Views

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08:32 min

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July 13, 2017

DOI:

10.3791/55770-v

DOI:
10.3791/55770-v

•

08:32 min
July 13, 2017

•

19 Views
, , , , , , , , , , , , ,
1Neuroregeneration Laboratory, Department of Anesthesiology,University of California, San Diego, 2Institute of Animal Physiology and Genetics,Czech Academy of Sciences, 3Department of Neurosurgery,University of California, San Diego, 4Institute of Neurobiology,Slovak Academy of Sciences

Özet

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본 연구의 목적은 성인 생쥐에서 새로운 subpial 유전자 전달 기술을 사용하여 척수 adeno-associated virus 9 (AAV9) 매개 유전자 전달의 효능과 안전성을 개발하고 검증하는 것이었다.

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Tadokoro, T., Miyanohara, A., Navarro, M., Kamizato, K., Juhas, S., Juhasova, J., Marsala, S., Platoshyn, O., Curtis, E., Gabel, B., Ciacci, J., Lukacova, N., Bimbova, K., Marsala, M. Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice. J. Vis. Exp. (125), e55770, doi:10.3791/55770 (2017).

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