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冷痛覚のための新規アッセイ<em>ショウジョウバエ</em>幼虫

JoVE Journal
Nörobilim

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JoVE Journal Nörobilim

Novel Assay for Cold Nociception in Drosophila Larvae

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冷痛覚のための新規アッセイ<em>ショウジョウバエ</em>幼虫

7,577 Views

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06:52 min

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April 03, 2017

DOI:

10.3791/55568-v

DOI:

10.3791/55568-v

•

06:52 min

April 03, 2017

•

7 Views

Heather N. Turner^1,2,5, Christian Landry³, Michael J. Galko^1,2,4

¹Genetik Bölümü,UT MD Anderson Cancer Center, ²Neuroscience Program,Graduate School of Biomedical Sciences at Houston, ³ProDev Engineering, ⁴Genes and Development Program,Graduate School of Biomedical Sciences at Houston, ⁵Section of Neurobiology,University of Southern California

Özet

ここでは、 ショウジョウバエの幼虫に冷たい痛覚を研究するための新規なアッセイを示しています。このアッセイは、焦点有害冷たい刺激を印加することが可能な特注のペルティエプローブを利用し、定量化可能な冷たい固有の動作になります。この技術は冷たい痛覚の更なる細胞および分子解剖を許可します。

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