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Microglies comme un biocapteur Surrogate pour déterminer Nanoparticules neurotoxicité
JoVE Journal
Nörobilim
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JoVE Journal Nörobilim
Microglia as a Surrogate Biosensor to Determine Nanoparticle Neurotoxicity

Microglies comme un biocapteur Surrogate pour déterminer Nanoparticules neurotoxicité

DOI:

08:37 min

October 25, 2016

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Bölümler

  • 00:05Başlık
  • 01:12Culturing Microglial Cells
  • 03:47Measuring Cytokine Release from Microglial Cells
  • 05:42Using Cultured Hypothalamic Cells for a Toxicity Assay
  • 06:57Results: Cytokine Release from Microglial after AgNP Exposure
  • 07:54Conclusion

Özet

Otomatik Çeviri

Microglia (immune cells of the brain), are used as a surrogate biosensor to determine how nanoparticles influence neurotoxicity. We describe a series of experiments designed to assay microglial response to nanoparticles and exposure of hypothalamic neurons to supernatant from activated microglia to determine neurotoxicity.

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