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在多发性硬化症的小鼠模型测量进行性神经功能残疾
JoVE Journal
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JoVE Journal Nörobilim
Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis
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在多发性硬化症的小鼠模型测量进行性神经功能残疾

DOI:
10.3791/54616-v

•

08:11 min

•

November 14, 2016

•

, ,
1Department of Neurology,Geisel School of Medicine at Dartmouth

Bölümler

  • 00:05Başlık
  • 01:14Rotarod Training
  • 03:08Mouse TMEV Infection
  • 04:37Rotarod Experiment
  • 06:12Results: Rotarod Performance Test Shows Lower NFI Values in TMEV-infected MIce Compared to Sham-controls
  • 07:02Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

An optimized testing protocol is presented in this paper for the Rotarod performance test, used for measuring progressive neurological disability in TMEV-infected mice.

Etiketler

Mouse ModelMultiple SclerosisProgressive Neurological DisabilityRotarod TestTheilers VirusMotor FunctionBalance CoordinationAcclimationTraining ProtocolTime To FallTrials

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