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の応用<em>インビボ</em組織工学骨格筋の修復を評価するためのラット前脛骨の>機能テスト
JoVE Journal
Biyomühendislik
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JoVE Journal Biyomühendislik
Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair
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の応用<em>インビボ</em組織工学骨格筋の修復を評価するためのラット前脛骨の>機能テスト

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07:13 min

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October 07, 2016

DOI:

10.3791/54487-v

DOI:
10.3791/54487-v

•

07:13 min
October 07, 2016

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1Patoloji Bölümü,University of Virginia, 2Department of Biomedical Engineering,University of Virginia, 3Department of Orthopaedic Surgery,University of Virginia

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We describe an in vivo protocol to measure dorsiflexion of the foot following stimulation of the peroneal nerve and contraction of the anterior crural compartment of the rat hindlimb. Such measurements are an indispensable translational tool for evaluating skeletal muscle pathology and tissue engineering approaches to muscle repair and regeneration.

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Mintz, E. L., Passipieri, J. A., Lovell, D. Y., Christ, G. J. Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair. J. Vis. Exp. (116), e54487, doi:10.3791/54487 (2016).

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