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心筋の構造、機能の in vivo定量的評価では 、灌流および生存率は、心臓マイクロコンピュータ断層撮影法を使用しました
JoVE Journal
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JoVE Journal Biyomühendislik
In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
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心筋の構造、機能の in vivo定量的評価では 、灌流および生存率は、心臓マイクロコンピュータ断層撮影法を使用しました

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08:13 min

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February 16, 2016

DOI:

10.3791/53603-v

DOI:
10.3791/53603-v

•

08:13 min
February 16, 2016

•

11 Views
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1Genetik Bölümü,Erasmus MC, Rotterdam, 2Department of Experimental Cardiology,Erasmus MC, Rotterdam, 3PerkinElmer, Inc., 4Department of Vascular Surgery,Erasmus MC, Rotterdam, 5Radyasyon Onkoloji Bölümü,Erasmus MC, Rotterdam

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This method outlines the use of Quantum Micro-Computed Tomography (MicroCT) to assess cardiac morphology, function, perfusion, metabolism and viability with iodinated contrast agent in mice with experimentally-induced myocardial ischemia. The technique can be applied for non-destructive high-throughput longitudinal in vivo imaging of various animal models of human heart disease.

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van Deel, E., Ridwan, Y., van Vliet, J. N., Belenkov, S., Essers, J. In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography. J. Vis. Exp. (108), e53603, doi:10.3791/53603 (2016).

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