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Frühe das Eindringen des Virus-Assays für die Ermittlung und Bewertung von antiviralen Verbindungen

JoVE Journal
İmmünoloji ve Enfeksiyon

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JoVE Journal İmmünoloji ve Enfeksiyon

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds

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Frühe das Eindringen des Virus-Assays für die Ermittlung und Bewertung von antiviralen Verbindungen

29,738 Views

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09:29 min

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October 29, 2015

DOI:

10.3791/53124-v

DOI:

10.3791/53124-v

•

09:29 min

October 29, 2015

•

25 Views

Chen-Jei Tai^1,2, Chia-Lin Li³, Cheng-Jeng Tai^4,5, Chien-Kai Wang^2,4, Liang-Tzung Lin^3,6

¹Department of Chinese Medicine,Taipei Medical University Hospital, ²Department of Obstetrics and Gynecology, School of Medicine, College of Medicine,Taipei Medical University, ³Department of Microbiology and Immunology, School of Medicine, College of Medicine,Taipei Medical University, ⁴Division of Hematology and Oncology, Department of Internal Medicine,Taipei Medical University Hospital, ⁵Department of Internal Medicine, School of Medicine, College of Medicine,Taipei Medical University, ⁶Graduate Institute of Medical Sciences, College of Medicine,Taipei Medical University

Özet

Here, we present a protocol that examines specific steps of the viral entry to identify and evaluate novel antiviral agents.

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Key Words:- Viral Entry Assays- Antiviral Compounds- Cell-based Systems- Viral Life Cycle- Viral Entry Stages- Viral Inactivation- Viral Attachment- Viral Entry/fusion- Hepatitis C Virus- Antiviral Assays- Antagonists- Inhibitors- Early Viral Entry- Drug Development

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