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A Method for Remotely Silencing Neural Activity in Rodents During Discrete Phases of Learning
JoVE Journal
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JoVE Journal Davranış
A Method for Remotely Silencing Neural Activity in Rodents During Discrete Phases of Learning

A Method for Remotely Silencing Neural Activity in Rodents During Discrete Phases of Learning

14,481 Views

09:22 min

June 22, 2015

DOI:

09:22 min
June 22, 2015

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Özet

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This protocol describes how to temporarily and remotely silence neuronal activity in discrete brain regions while rats are engaged in learning and memory tasks. The approach combines pharmacogenetics (Designer-Receptors-Exclusively-Activated-by-Designer-Drugs) with a behavioral paradigm (sensory preconditioning) that is designed to distinguish between different components of learning.

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