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Nest Building as an Indicator of Health and Welfare in Laboratory Mice
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Nest Building as an Indicator of Health and Welfare in Laboratory Mice

Nest Building as an Indicator of Health and Welfare in Laboratory Mice

25,765 Views

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06:12 min

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December 24, 2013

DOI:

10.3791/51012-v

DOI:
10.3791/51012-v

•

06:12 min
December 24, 2013

•

35 Views
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1Research Models and Services,Charles River, 2Department of Clinical Sciences,Tufts University, 3Department of Comparative Medicine,Stanford University, 4Department of Psychiatry and Behavioral Sciences,Stanford University

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We demonstrate the utility of nest building behavior in laboratory mice as an indicator of welfare. Nest scoring is a sensitive technique that is altered by temperature, illness, and aggression. The time to integrate into nest test (TINT) is a simple cage-side assessment that can detect postoperative pain.

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Nest BuildingWelfare IndicatorLaboratory MiceDistress AssessmentPhysiological IndicatorsBehavioral IndicatorsCage-side AssessmentThermal StressAggressionSicknessPain

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Cite this Article

Gaskill, B. N., Karas, A. Z., Garner, J. P., Pritchett-Corning, K. R. Nest Building as an Indicator of Health and Welfare in Laboratory Mice. J. Vis. Exp. (82), e51012, doi:10.3791/51012 (2013).

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