This content is Free Access.
In vivo herprogrammeren van volwassen lichaamscellen te Pluripotentie door overexpressie van Yamanaka Factors
12,428 Views
•
12:12 min
•
December 17, 2013
DOI:
Özet
Automatically generated
This study demonstrates the reprogramming of somatic cells towards pluripotency in vivo without the generation of teratomas. We used hydrodynamic tail vein injection of plasmid DNA encoding the Yamanka factors to induce the in vivo reprogramming of adult hepatocytes into cells of enhanced pluripotency.
Read Article
Cite this Article
Yilmazer, A., de Lázaro, I., Bussy, C., Kostarelos, K. In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors. J. Vis. Exp. (82), e50837, doi:10.3791/50837 (2013).
Copy