This content is Free Access.
A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice
42,748 Views
•
07:07 min
•
May 10, 2013
DOI:
Özet
Automatically generated
Measurement of glomerular filtration rate (GFR) is the gold standard for kidney function assessment. Here we describe a high-throughput method which allows the determination of GFR in conscious mice by using a single bolus injection, determination of fluorescein isothiocyanate (FITC)-inulin in plasma and calculation of GFR by a two-phase exponential decay model.
Read Article
Cite this Article
Rieg, T. A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice. J. Vis. Exp. (75), e50330, doi:10.3791/50330 (2013).
Copy