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Immunogenicity Enhancement by Mycobacterium paratuberculosis in Autoimmune Encephalomyelitis

Immunogenicity Enhancement by Mycobacterium paratuberculosis in Autoimmune Encephalomyelitis

May 12, 2023

Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

02:51 min
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Mycobacterial Antigen Preparation

01:38 min
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249 Views

Preparation and Injection of Myelin Oligodendrocyte Glycoprotein (MOG35-55) Emulsion

03:05 min
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346 Views
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1Department of Neurology,Juntendo University, 2Biomedical Research Core Facilities,Juntendo University, 3Neurodegenerative Disorders Collaborative laboratory,RIKEN Center for Brain Science

Özet

Here, we present an alternative protocol to actively induce experimental autoimmune encephalomyelitis in C57BL/6 mice, using the immunogenic epitope myelin oligodendrocyte glycoprotein (MOG)35-55 suspended in incomplete Freund’s adjuvant containing the heat-killed Mycobacterium avium subspecies paratuberculosis.

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