Potentiodynamische Korrosionsprüfung
Summary
Here, we present a protocol to set up and run an in vitro potentiodynamic corrosion system to analyze pitting corrosion for small metallic medical devices.
Abstract
Different metallic materials have different polarization characteristics as dictated by the open circuit potential, breakdown potential, and passivation potential of the material. The detection of these electrochemical parameters identifies the corrosion factors of a material. A reliable and well-functioning corrosion system is required to achieve this.
Corrosion of the samples was achieved via a potentiodynamic polarization technique employing a three-electrode configuration, consisting of reference, counter, and working electrodes. Prior to commencement a baseline potential is obtained. Following the stabilization of the corrosion potential (Ecorr), the applied potential is ramped at a slow rate in the positive direction relative to the reference electrode. The working electrode was a stainless steel screw. The reference electrode was a standard Ag/AgCl. The counter electrode used was a platinum mesh. Having a reliable and well-functioning in vitro corrosion system to test biomaterials provides an in-expensive technique that allows for the systematic characterization of the material by determining the breakdown potential, to further understand the material’s response to corrosion. The goal of the protocol is to set up and run an in vitro potentiodynamic corrosion system to analyze pitting corrosion for small metallic medical devices.
Introduction
Elektrochemische Techniken bieten eine schnelle und relativ kostengünstige Verfahren die elektrochemische Eigenschaften eines Materials zu erhalten. Diese Techniken basieren hauptsächlich auf der Fähigkeit , durch Beobachten der Reaktion des Ladungstransferprozesses auf eine kontrollierte elektrochemische Störung 1-5 Korrosion eines Metalls zu erfassen. Die Korrosion von Metallimplantaten in einem Körperumgebung ist entscheidend aufgrund der negativen Auswirkungen auf die Biokompatibilität und Materialintegrität 6. Der Hauptfaktor , um die Korrosion von Implantaten innerhalb des Körpers beiträgt , ist die Auflösung der Oxidoberfläche zu einer erhöhten Freisetzung von Metallionen führen 7-11. Dies führt zu unerwünschten biologischen Reaktionen, die lokal gefunden werden kann, jedoch mit potentiell systemische Wirkung zum vorzeitigen Versagen des Implantats führen 10,12-28.
Die Korrosionseigenschaften eines Prüflings aus dem Polarisations Scan vorhergesagt erzeugtdurch einen Potentiostaten. Ein Polarisations Scan ermöglicht die Extrapolation der kinetischen und Korrosionsparameter eines Metallsubstrats. Während einer Abtastung, die Oxidation oder Reduktion einer elektroaktiven Spezies kann durch Ladungsübertragung und der Bewegung der Reaktanten oder Produkte beschränkt. Diese Faktoren sind alle von der Polarisations Scan verkapselt; daher wichtig, ein System zu haben, das eine zuverlässige und wiederholbare Polarisations Abtastung über mehrere Zyklen erzeugt, ist von großer Bedeutung. Der Schwerpunkt dieses Manuskripts ist ein Protokoll zur Verfügung, aus denen die Grundlagen und Schritte, um eine gut funktionierende potentiodynamischer Korrosionssystem zu erhalten genommen.
Protocol
Representative Results
Discussion
Polarisations – Scans von den Proben aus rostfreiem Stahl hergestellt zeigte saubere kontinuierliche Plots mit Scans Korrelation in der Literatur gesehen, das einen gut funktionierenden Korrosionssystem , das sowohl zuverlässig und reproduzierbar 29 ist. Schlechte Reproduzierbarkeit von potentiodynamischen Pitting Potentialen mit einer Ausbreitung von einigen hundert Millivolt identifiziert, mit 29 durch einen stochastischen Prozess gekennzeichnet Potential liegen Grübchenbildung. Dies ist häufi…
Disclosures
The authors have nothing to disclose.
Acknowledgements
The authors had no funding provided for this study.
Materials
| Potentiostat | Metrohm | PGSTAT101 | |
| Ag/AgCl reference electrode, shielded | Metrohm | 6.0729.100 | |
| Electrode shaft | Metrohm | 6.1241.060 | |
| Polisher Forcipol 1v | Metkon | 3602 | |
| Clindrical flask 700mL | SciLabware | FR700F | |
| Reaction lid | SciLabware | MAF2/41 | |
| Dichloromethane | Sigma-Aldrich | MKBR7629V | use under a fumehood. Wear protective clothing |
| Thermo / HAAKE D Series Immersion Circulators | Haake |
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